Admixture Runs (SGDP Plus)

[ Raw: I ] [ With Maf / LD Pruning: II ] [ With Maf / LD Pruning / Geno: III: K 2 ] [ III: K 11 ] [ III: K 20 ] [ III: K 40 ] [ III: K 50 ] [ III: K 64 ] [ III: K Overclustering ] [ With SGDP Plus: IV: K 40, 50, 64 ]

 

I. Adding Samples to SGDP

SGDP = Mallick et al. 2016, "The Simons Genome Diversity Project. 300 genomes from 142 diverse populations", in: "Nature", 2016 Oct 13, Vol. 538, No. 7624, pp. 201-206, doi: 10.1038/nature18964, pubmed.ncbi.nlm.nih.gov.

AADR = Mallick et al. 2024, "The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes", in: "Sci Data", Vol. 11, No. 182, dataverse.harvard.edu.

345 samples (129 females, 179 males, 37 ambiguous; 345 founders) loaded from sgdp/cteam_extended.v4.maf0.1perc.psam. 34418131 variants loaded from sgdp/cteam_extended.v4.maf0.1perc.pvar.

 

Adding Erfurt_ME

"We used K-means to cluster the EAJ individuals based on their PC1 and PC2 coordinates into two groups. One group, which we call 'Erfurt-EU', falls closer to individuals from European populations, while the other, which we call 'Erfurt-ME', is closer to Middle Eastern populations" (Waldman et al. 2022, "Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14th century", in: "Cell", Volume 185, Issue 25, 8 December 2022, Pages 4703-4716.e16).

Solo: Total genotyping rate is 0.377819. 1232738 variants and 13 people pass filters and QC.
Integration: 34548187 variants loaded from .bim file. 358 people (182 males, 139 females, 37 ambiguous) loaded from .fam. Total genotyping rate is 0.958619.

Data S2, Table 1: The characteristics of the Erfurt samples (only Erfurt-ME)
Sample Grave SNPs on autosomes Sex Estimated age Subgroup Family Y chromosome - a Y terminal (YFull) - b Nearest common AJ Y lineage mtDNA haplogroup mtDNA terminal (YFull) b 14C dates (95.4% probability)
I13861 25 325256 F 25-35 Erfurt-ME No - K1a1b1a K1a1b1a
I13863 21 263504 F 18-25 Erfurt-ME No - K1a9 K1a9 -
I13864 36 674768 M 35-50 Erfurt-ME No J2a1a1a2b2(xJ2a1a1a2b2a1) J-Y15223 J-Y15234 H3p H3p1 -
I13865 44 548027 M 18-25 Erfurt-ME No R1b1a1b1b R-Y19847 (xY143993) R-Y19869 L2a1l2a L2a1l2a -
I13867 45 777554 F 50+ Erfurt-ME No - K1a1b1a K1a1b1a -
I13870 5 363232 M 45-60 Erfurt-ME No J2a1a1a2b2a J-Y95077 J-L556 K1a1b1a K1a1b1a -
I14736 68 681500 F - Erfurt-ME No - K1a1b1a K1a1b1a -
I14737 57 383429 F 8-11 Erfurt-ME No - N1b1b1 N1b1b1 1296-1394 calCE
I14739 60 326400 F 40-60 Erfurt-ME No - H5c2 H5c2a1 -
I14741 * 123772 F 16-20 Erfurt-ME No - K1a1b1a K1a1b1a 1285-1389 calCE
I14851 20 435908 F 12-15 Erfurt-ME No - K1a1b1a K1a1b1a 1301-1397 calCE
I14852 41 250663 F 60+ Erfurt-ME No - H6a1a1a H6a1a1a1 -
I14903 47 598350 F 35-50 Erfurt-ME No - K1a1b1a K1a1b1a -

* 13/133-140 (Grave marked as possible stray find).

 

Adding German / Irish-Norman

ADN001.A bis ADN015.A = Lower Saxony, Hannover-Anderten, ENA-Project: PRJEB54899, aus: Gretzinger et al 2022: "The Anglo-Saxon migration and the formation of the early English gene pool", in: "Nature", Vol. 610, No. 112-119, 2022, doi.org/10.1038/s41586-022-05247-2.

Nach aadr_v54.1.p1_1240K_public.ind (The Allen Ancient DNA Resource AADR, Dataverse 8.0, March 6 2023): 11x Germany_Anderten_Saxon_Medieval.

KIL001.B_noUDG bis KIL047.B_noUDG = Ireland, Kliteasheen, ENA-Project: PRJEB54899.

Nach aadr_v54.1.p1_1240K_public.ind (The Allen Ancient DNA Resource AADR, Dataverse 8.0, March 6 2023): 38x Ireland_Kilteasheen_AngloSaxon_EMedieval_Norman.

Solo: Total genotyping rate is 0.523189. 1233013 variants and 49 people pass filters and QC.
Integration: 34547912 variants loaded from .bim file. 407 people (218 males, 152 females, 37 ambiguous) loaded from .fam. Total genotyping rate is 0.845471.

 

Adding Tàrrega

"In the Roquetes necropolis of Tàrrega, six communal graves containing at least sixty-nine individuals, with signs of violence, were dated to the mid-14th century. Based on the hypothesis that Iberian medieval Jewish communities preserve genetic similarities to other ancient and modern Jewish communities, our study aims to provide genomic information on medieval Iberian communities, which to date have been unknown" (Pallarés-Viña et al. 2026, "Uncovering a Medieval Pogrom: Genetic History of a Jewish Community in Catalonia (Spain)", in: "Genes" 2026, Vol. 17, No. 3, p. 358).

 

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